Relevant publications and presentations

Consortium

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.
Nat Genet. 2007. PMID: 17952073 DOI: 10.1038/ng.2007.17
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
Wellcome Trust Case Control Consortium
Nature. 2007;447;661-78. PMID: 17554300 DOI: 10.1038/nature05911

Single disease

Genomewide association analysis of coronary artery disease.
Samani NJ, Erdmann J, Hall AS, Hengstenberg C, Mangino M, Mayer B, Dixon RJ, Meitinger T, Braund P, Wichmann HE, Barrett JH, König IR, Stevens SE, Szymczak S, Tregouet DA, Iles MM, Pahlke F, Pollard H, Lieb W, Cambien F, Fischer M, Ouwehand W, Blankenberg S, Balmforth AJ, Baessler A, Ball SG, Strom TM, Braenne I, Gieger C, Deloukas P, Tobin MD, Ziegler A, Thompson JR, Schunkert H,
N Engl J Med. 2007;357;443-53. PMID: 17634449 DOI: 10.1056/NEJMoa072366
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.
Parkes M, Barrett JC, Prescott NJ, Tremelling M, Anderson CA, Fisher SA, Roberts RG, Nimmo ER, Cummings FR, Soars D, Drummond H, Lees CW, Khawaja SA, Bagnall R, Burke DA, Todhunter CE, Ahmad T, Onnie CM, McArdle W, Strachan D, Bethel G, Bryan C, Lewis CM, Deloukas P, Forbes A, Sanderson J, Jewell DP, Satsangi J, Mansfield JC, , Cardon L, Mathew CG
Nat Genet. 2007;39;830-2. PMID: 17554261 DOI: 10.1038/ng2061
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.
Todd JA, Walker NM, Cooper JD, Smyth DJ, Downes K, Plagnol V, Bailey R, Nejentsev S, Field SF, Payne F, Lowe CE, Szeszko JS, Hafler JP, Zeitels L, Yang JH, Vella A, Nutland S, Stevens HE, Schuilenburg H, Coleman G, Maisuria M, Meadows W, Smink LJ, Healy B, Burren OS, Lam AA, Ovington NR, Allen J, Adlem E, Leung HT, Wallace C, Howson JM, Guja C, Ionescu-Tîrgovişte C, , Simmonds MJ, Heward JM, Gough SC, , Dunger DB, Wicker LS, Clayton DG
Nat Genet. 2007;39;857-64. PMID: 17554260 DOI: 10.1038/ng2068
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
Zeggini E, Weedon MN, Lindgren CM, Frayling TM, Elliott KS, Lango H, Timpson NJ, Perry JR, Rayner NW, Freathy RM, Barrett JC, Shields B, Morris AP, Ellard S, Groves CJ, Harries LW, Marchini JL, Owen KR, Knight B, Cardon LR, Walker M, Hitman GA, Morris AD, Doney AS, Wellcome Trust Case Control Consortium (WTCCC), McCarthy MI, Hattersley AT
Science. 2007;316;1336-41. PMID: 17463249 DOI: 10.1126/science.1142364
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.
Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM, Lindgren CM, Perry JR, Elliott KS, Lango H, Rayner NW, Shields B, Harries LW, Barrett JC, Ellard S, Groves CJ, Knight B, Patch AM, Ness AR, Ebrahim S, Lawlor DA, Ring SM, Ben-Shlomo Y, Jarvelin MR, Sovio U, Bennett AJ, Melzer D, Ferrucci L, Loos RJ, Barroso I, Wareham NJ, Karpe F, Owen KR, Cardon LR, Walker M, Hitman GA, Palmer CN, Doney AS, Morris AD, Smith GD, Hattersley AT, McCarthy MI
Science. 2007;316;889-94. PMID: 17434869 DOI: 10.1126/science.1141634

Methodological papers

A new multipoint method for genome-wide association studies by imputation of genotypes.
Marchini J, Howie B, Myers S, McVean G, Donnelly P
Nat Genet. 2007;39;906-13. PMID: 17572673 DOI: 10.1038/ng2088
Detecting disease associations due to linkage disequilibrium using haplotype tags: a class of tests and the determinants of statistical power.
Chapman JM, Cooper JD, Todd JA, Clayton DG
Hum Hered. 2003;56;18-31. PMID: 14614235 DOI: 10.1159/000073729

Posters

Large scale genomewide association analysis of multiple disease phenotypes: the Wellcome Trust Case Control Consortium.
McCarthy MI
American Society of Human Genetics (PDF).